This study of 52 predominantly lower income Jordanian and Syrian families with young children (31 girls; Mage = 53.37 months, SD = 3.53) in Jordan began in 2019, before the pandemic. Families were followed to explore stress physiology, family functioning, and mental health over the first 9 months of the pandemic. Mothers reported less adaptive coping and more negative changes to family life in June 2020 when their children had poorer behavioral self-regulation and more behavior problems, and when families had lower income, in 2019. More negative changes to family life predicted greater hair cortisol concentrations in children in June 2020, and more negative changes and less adaptive coping predicted worse child and mother psychosocial adjustment in December 2020.

An estimated 12 million girls aged 15–19 years, and 777,000 girls younger than 15 give birth globally each year. Contexts of war and displacement increase the likelihood of early marriage and childbearing. Given the developmentally sensitive periods of early childhood and adolescence, adolescent motherhood in conflict-affected contexts may put a family at risk intergenerationally. We propose that the specifics of normative neuroendocrine development during adolescence, including increased sensitivity to stress, pose additional risks to adolescent girls and their young children in the face of war and displacement, with potential lifelong consequences for health and development. This paper proposes a developmental, dual-generational framework for research and policies to better understand and address the needs of adolescent mothers and their small children. We draw from the literature on developmental stress physiology, adolescent parenthood in contexts of war and displacement internationally, and developmental cultural neurobiology. We also identify culturally meaningful sources of resilience and provide a review of the existing literature on interventions supporting adolescent mothers and their offspring. We aim to honor Edward Zigler's groundbreaking life and career by integrating basic developmental science with applied intervention and policy.